generic for Oracea

What is Doxycycline?

Common Brand(s): Acticlate, Monodox, Vibra-Tabs, Vibramycin

This medication is used to treat a wide variety of bacterial infections, including those that cause acne. This medication is also used to prevent malaria. This medication is known as a tetracycline antibiotic. It works by stopping the growth of bacteria.

This antibiotic treats only bacterial infections. It will not work for viral infections (such as common cold, flu). Using any antibiotic when it is not needed can cause it to not work for future infections.


  • cholera
  • plague
  • tularemia
  • inhaled anthrax
  • gastrointestinal anthrax
  • post-exposure anthrax prevention
  • brucellosis
  • listeriosis
  • atypical mycobacterial infection
  • actinomycosis
  • Campylobacter fetus infection
  • psittacosis
  • trachoma
  • inclusion conjunctivitis caused by Chlamydia trachomatis
  • chlamydial infections
  • louse-borne typhus
  • murine typhus
  • recrudescent typhus
  • scrub typhus
  • typhus infections
  • Rocky Mountain spotted fever
  • Q fever
  • rickettsialpox
  • rickettsial infection
  • chloroquine-resistant Plasmodium falciparum malaria
  • chloroquine-resistant Plasmodium falciparum malaria prevention
  • Plasmodium vivax malaria prevention
  • malaria
  • malaria prevention
  • relapsing fever
  • bartonellosis
  • Lyme disease
  • Lyme arthritis
  • syphilis
  • acute lower genitourinary gonorrhea
  • acute gonococcal urethritis
  • acute gonococcal epididymo-orchitis
  • acute gonococcal cervicitis
  • acute gonococcal endometritis
  • gonococcal pharyngitis
  • rectal gonorrhea
  • disseminated gonococcal infection
  • chancroid
  • lymphogranuloma venereum
  • granuloma inguinale
  • rectal Chlamydia trachomatis infection
  • genitourinary Chlamydia trachomatis infection
  • yaws
  • ocular rosacea
  • pharyngitis
  • upper respiratory pneumococcal infection
  • sinusitis
  • acute Staph. aureus sinusitis
  • bacterial pneumonia
  • mycoplasmal pneumonia
  • gingivostomatitis
  • periodontitis adjunct therapy
  • enterocolitis
  • Chlamydial epididymitis
  • skin and skin structure infection
  • acne rosacea
  • acne vulgaris
  • lyme disease prevention
  • nongonococcal urethritis
  • cutaneous anthrax
  • postexposure plague prophylaxis
  • ehrlichiosis
  • leptospirosis
  • bacterial urinary tract infection
  • boutonneuse fever
  • severe malaria
  • Q fever endocarditis

Usage Instructions

Read the Patient Information Leaflet if available from your pharmacist before you start taking doxycycline and each time you get a refill. If you have any questions, ask your doctor or pharmacist.

This medication is best taken by mouth on an empty stomach, at least 1 hour before or 2 hours after a meal, usually 1 or 2 times daily or as directed by your doctor. Take this medication with a full glass of water (8 ounces/240 milliliters) unless directed otherwise. If stomach upset occurs, taking it with food or milk may help. However, doxycycline may not work as well if you take it with food or milk (or anything high in calcium - more details below ), so ask your doctor or pharmacist if you may take it that way. Do not lie down for at least 10 minutes after taking this medication.

Take this medication 2 to 3 hours before or after taking any products containing aluminum, calcium, iron, magnesium, zinc, or bismuth subsalicylate. Some examples include antacids, didanosine solution, quinapril, vitamins/minerals, dairy products (such as milk, yogurt), and calcium-enriched juice. These products bind with doxycycline, preventing your body from fully absorbing the drug.

When using to prevent malaria, this medication is usually taken once daily. Take the first dose of this medication 1 to 2 days before travel or as directed by your doctor. Continue to take this medication daily while in the malarious area. Upon returning home, you should keep taking this medication for 4 more weeks. If you are unable to finish this course of doxycycline, contact your doctor.

If you are using the liquid form of this medication, shake the bottle well before each dose. Carefully measure the dose using a special measuring device/spoon. Do not use a household spoon because you may not get the correct dose.

The dosage is based on your medical condition and response to treatment. For children, the dosage may also be based on weight.

For the best effect, take this antibiotic at evenly spaced times. To help you remember, take this medication at the same time(s) every day.

Continue to take this medication until the full prescribed amount is finished, even if symptoms disappear after a few days. Stopping the medication too early may allow bacteria to continue to grow, which may result in a return of the infection.

Tell your doctor if your condition persists or worsens.


Store at room temperature away from light and moisture. Different brands of this medication have different storage needs. Check the product package for instructions on how to store your brand, or ask your pharmacist. Do not store in the bathroom. Keep all medications away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Taking outdated tetracycline-related drugs can result in serious illness. Consult your pharmacist or local waste disposal company.