The Cost of Eliquis Without Insurance

Prescription Drugs

The Cost of Eliquis Without Insurance

Jennifer Hadley
By Jennifer Hadley
Oct 20, 2020 - Updated Apr 20, 2021
Carina Fung, PharmD, BCPPS
Medically Reviewed ByCarina Fung, PharmD, BCPPS
Someone pouring Eliquis from a pill holder onto their hand.

The CDC reports that 900,000 Americans are affected by blood clots each year, resulting in almost 100,000 deaths. Blood clots can occur in multiple areas of the body including the lower leg, thigh, pelvis, or arm.

If left untreated, part of the blood clot may break off, leading to a stroke or pulmonary embolism. Fortunately, anticoagulation medication such as Eliquis can help to prevent blood clots. Here are answers to common questions about Eliquis, including tips for managing the cost of Eliquis without insurance.

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How much does Eliquis cost without insurance?

The cost of Eliquis without insurance starts at $$255.92* for 5mg and 30 tablets using an RxSaver coupon.

Eliquis is a brand name drug. Although two generics have been granted FDA approval, the generics are not yet available. Until a generic is released, the cost of Eliquis without insurance can cause a severe financial burden for many individuals.

RxSaver prescription drug coupons or prescription assistance programs such as the RxSaver Advocacy Program may offer significant savings on medications such as Eliquis.

In addition, savings on Eliquis may be possible through manufacturer coupons, such as the Eliquis Savings & Support Program.

RxSaver Rx Advocacy Program

The Rx Advocacy Program from RxSaver is a prescription assistance program. It was created to help those who require high-cost prescription drugs and cannot afford them, regardless of income or insurance. Contact a representative to determine if you qualify.

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What is Eliquis?

Eliquis is an anticoagulant, also occasionally called a blood thinner. However, Eliquis actually doesn’t affect the thickness or viscosity of your blood. Instead, it lengthens the amount of time it takes for a blood clot to form. It is commonly prescribed to individuals who have been diagnosed with atrial fibrillation (AFib), those who suffer from deep vein thrombosis (DVT) and to prevent blood clots in those who have had surgeries such as hip or knee replacements.

What conditions does Eliquis treat?

Eliquis is used to prevent the formation of potentially dangerous blood clots, which can lead to a stroke in those who have AFib. It is also used to prevent recurrences of blood clots in those who have experienced DVT and those who have had a pulmonary embolism. Eliquis is also used to prevent blood clots in patients who have undergone joint replacement surgeries.

Common Symptoms of Atrial Fibrillation

AFib is an irregular heartbeat, which causes the top chambers of the heart to fibrillate (quiver or shake). Atrial fibrillation is very common. Many individuals who have AFib do not have any symptoms. Others who are ultimately diagnosed with AFib may experience symptoms such as:

  • Fatigue
  • Weakness
  • Dizziness
  • Feeling faint
  • Chest pain
  • Chest pressure
  • Rapid heartbeat
  • Shortness of breath
  • Sweating

Common Symptoms of Deep Vein Thrombosis

A blood clot that forms in a vein deep in the body is called a deep vein thrombosis, or DVT. DVT forms most often in the leg, thigh, or pelvis. DVT is dangerous and potentially fatal, because the blood clot may break free, and get stuck in a blood vessel. You should contact your healthcare provider right away if you have any symptoms of DVT, which include:

  • Swelling in an arm or leg, with no obvious cause
  • Enlarged veins
  • Blue or red-looking skin
  • Warmth in the arm, leg, or other areas, accompanied by pain
  • Pain when you stand or walk

Common Symptoms of Pulmonary Embolism

A pulmonary embolism (PE) occurs when a blood clot gets lodged in a blood vessel of the lung. Pulmonary embolism can be fatal, which is why it is important to see a health care provider if you experience any symptoms of deep vein thrombosis. If you have symptoms of a pulmonary embolism, contact your medical emergency services immediately. Symptoms of a pulmonary embolism include:

  • Chest pain that worsens if you take a deep breath
  • Shortness of breath
  • Rapid/increased heartbeat (palpitations)
  • Coughing up blood
  • Dizziness, lightheadedness
  • Blue lips or nails
  • Sweating more than normal

How does Eliquis work?

The active ingredient in Eliquis is called apixaban. Apixaban is an inhibitor of an enzyme (FXa) that plays a crucial role in forming substances that cause blood clotting. As such Eliquis belongs to a class of drugs known as factor Xa inhibitors, commonly called anticoagulants. In short, apixaban makes it less likely that blood will clot.

Common Side Effects of Eliquis

Common side effects of Eliquis involve changes in bleeding, and you should notify your healthcare provider if you experience any of the following:

  • Bleeding that will not stop
  • Unusual bleeding (rectum, nose, mouth, vagina)
  • Red, brown, pink urine
  • Blood in stool
  • Heavy menstrual periods
  • Blood in vomit
  • Coughing up blood

Other side effects from Eliquis may include

  • Nausea
  • Headache
  • Fainting
  • Dizziness
  • Muscle weakness
  • Numbness
  • Lightheadedness
  • Tingling in legs or feed

Notify your health care provider of any side effects you experience from Eliquis, as it may be necessary to adjust your dosage, or change medications.

Can you buy Eliquis over the counter?

You cannot buy Eliquis over the counter. You need a prescription from a health care provider and need to purchase the medication from a pharmacy.

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Always Check RxSaverBefore Filling a Prescription

Before filling a prescription for Eliquis, or any other brand name or generic prescription, look for coupons from RxSaver. RxSaver offers drug coupons for more than 6,000 medications. There is no cost to use RxSaver. RxSaver prescription coupons can be used in place of your insurance if the coupon price is lower than your insurance copay. RxSaver is also a helpful savings tool for those who do not have insurance.

Eliquis: 5mg / 30 tablets

*Lowest online price at national pharmacy chains Costco, CVS, RiteAid, Walgreens and Walmart as of 4/20/2021. Prices vary by location and pharmacy, see for actual pricing in your area.

Jennifer Hadley

Jennifer Hadley

Jen Hadley is a freelance writer and journalist based in Los Angeles, who writes extensively about the medical, legal, health care, and consumer products industries. Jen is a regular contributor to RxSaver.

Carina Fung, PharmD, BCPPS

Carina Fung, PharmD, BCPPS

Carina Fung, PharmD, BCPPS., is a pharmacist who earned her PharmD from St. John’s University in Queens, NY. She maintains an active practice, serving as a Board-Certified Pediatric Pharmacotherapy Specialist at a large metropolitan teaching hospital in New York City. Carina has also published in pharmacy journals and works as a consultant reviewing medical articles for publication.

The information on this site is generalized and is not medical advice. It is intended to supplement, not substitute for, the expertise and judgment of your healthcare professional. Always seek the advice of your healthcare professional with any questions you may have regarding a medical condition. Never disregard seeking advice or delay in seeking treatment because of something you have read on our site. RxSaver makes no warranty as to the accuracy, reliability or completeness of this information.

If you are in crisis or you think you may have a medical emergency, call your doctor or 911 immediately.