How Much Does Azithromycin Cost Without Insurance?


How Much Does Azithromycin Cost Without Insurance?

Cold & Flu Season.The Flu.Strep Throat
Jennifer Hadley
By Jennifer Hadley
Jun 21, 2021
Carina Fung, PharmD, BCPPS
Medically Reviewed ByCarina Fung, PharmD, BCPPS
How Much Does Azithromycin Cost Without Insurance?

Azithromycin is the generic form of the brand drug Zithromax. It is commonly known as a Z-Pak. Azithromycin is a prescription antibiotic medication that is used to treat various bacterial infections. As an FDA-approved treatment for certain bacterial infections, azithromycin is very affordable. Here is how much azithromycin costs without insurance, if you use an RxSaver coupon.

How much does azithromycin cost?

At many national retail pharmacies, azithromycin costs less than $20 for a full course of treatment when you use an RxSaver coupon. An RxSaver coupon can be used if you do not have insurance. It can also be used if you have insurance if the coupon price at a pharmacy near you is less than your insurance copay.

The RxSaver coupon price for azithromycin starts at $10.20* for 250 mg and 6 tablets

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What is azithromycin?

Azithromycin, the generic for Z-Pak, is a macrolide antibiotic used to treat a variety of bacterial infections. A Z-Pak is a convenient antibiotic that is taken for less than a week. Azithromycin is a great alternative to penicillin for individuals who are allergic to penicillin.

What conditions does azithromycin treat?

Azithromycin treats bacterial infections only. It will not treat a viral infection. Bacterial infections of the sinus, throat, lungs, ears, and eyes often respond well to azithromycin. Additionally, some sexually transmitted diseases (STDs) and traveler’s diarrhea are treated with azithromycin. Here are some of the common conditions azithromycin treats.

Acute Bacterial Bronchitis

Azithromycin may be prescribed if you have acute bronchitis or chronic bronchitis that worsens to the point of developing a bacterial infection. However, azithromycin will not treat bronchitis that develops from a virus such as the flu.

Bacterial Sinusitis

Azithromycin may be prescribed to treat sinusitis caused by a bacterial infection if you are allergic to penicillin. It will not treat the common cold or the flu. When prescribed for a bacterial sinus infection, you may only need to take azithromycin for three days.

Strep Throat

Penicillin is often the first-line treatment for strep throat. But if you’re allergic to penicillin, azithromycin is often the prescribed antibiotic. Azithromycin is FDA-approved for the treatment of strep throat.


Azithromycin is often used to treat tonsillitis caused by a bacterial infection. Tonsillitis is an inflammation of the tonsils that may be caused by a virus or bacteria. If you are allergic to penicillin, azithromycin is likely to be prescribed for tonsillitis.

Acute Ear Infections

Azithromycin may be prescribed for the treatment of acute otitis media, otherwise known as an ear infection. It is often prescribed to children with ear infections. Azithromycin is also available as a liquid for children.

Bacterial Eye Infections

Azithromycin eye drops are used to treat bacterial infections of the eye, including bacterial conjunctivitis, otherwise known as pink eye. It works by stopping the growth of bacteria responsible for pink, red, itchy, tearing eyes.


Azithromycin is used to treat the sexually transmitted disease (STD) chlamydia. If you’ve been diagnosed with chlamydia, often a single dose of azithromycin can clear the infection.

Bacterial Diarrhea

Bacterial diarrhea is caused by ingesting contaminated food or water. Also known as bacterial gastroenteritis, bacterial diarrhea is commonly associated with travel, and commonly called “travelers’ diarrhea”. If you’re diagnosed with bacterial diarrhea you may be prescribed azithromycin.

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Common Side Effects of Azithromycin

All medications have the potential to cause side effects. The most commonly reported side effects of azithromycin are typically mild. They will resolve on their own. Common side effects of azithromycin include:

  • Diarrhea
  • Headache
  • Nausea
  • Stomach pain
  • Vomiting

Serious side effects can occur. Be sure to notify your health care provider of any side effects you experience.

Can you buy azithromycin over the counter?

You cannot buy azithromycin over the counter in the U.S. You will need a prescription from your health care provider, and will need to fill the prescription at a pharmacy.

Always Check RxSaver Before Filling a Prescription

Before filling a prescription for azithromycin, or other medication, check RxSaver. RxSaver is free-to-use and easy-to-use. You do not need to join a membership. Simply type your medication into the search bar found on the RxSaver website or free mobile app.

You will see coupon pricing for azithromycin at various pharmacies near you. When you pick up your medication, show the coupon to the pharmacist for savings. If you’re picking your medication up through the pharmacy drive-thru, call ahead to provide the coupon code, or read the coupon code to the pharmacist at the drive-thru.

*Lowest online price at national pharmacy chains Costco, CVS, RiteAid, Walgreens and Walmart as of 6/21/2021. Prices vary by location and pharmacy, see for actual pricing in your area.

Jennifer Hadley

Jennifer Hadley

Jen Hadley is a freelance writer and journalist based in Los Angeles, who writes extensively about the medical, legal, health care, and consumer products industries. Jen is a regular contributor to RxSaver.

Carina Fung, PharmD, BCPPS

Carina Fung, PharmD, BCPPS

Carina Fung, PharmD, BCPPS., is a pharmacist who earned her PharmD from St. John’s University in Queens, NY. She maintains an active practice, serving as a Board-Certified Pediatric Pharmacotherapy Specialist at a large metropolitan teaching hospital in New York City. Carina has also published in pharmacy journals and works as a consultant reviewing medical articles for publication.

The information on this site is generalized and is not medical advice. It is intended to supplement, not substitute for, the expertise and judgment of your healthcare professional. Always seek the advice of your healthcare professional with any questions you may have regarding a medical condition. Never disregard seeking advice or delay in seeking treatment because of something you have read on our site. RxSaver makes no warranty as to the accuracy, reliability or completeness of this information.

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