Zolpidem ER

generic for Ambien CR

Zolpidem ER Side Effects

See also Warning section.

Dizziness may occur. If this effect persists or worsens, tell your doctor or pharmacist promptly.

This medication may make you sleepy during the day. Tell your doctor if you have daytime drowsiness. Your dose may need to be adjusted.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor right away if any of these unlikely but serious side effects occur: memory loss, mental/mood/behavior changes (such as new/worsening depression, abnormal thoughts, thoughts of suicide, hallucinations, confusion, agitation, aggressive behavior, anxiety).

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
  • palpitations
  • infection
  • anemia
  • acute confusion
  • panic disorder
  • depersonalization
  • suicidal ideation
  • libido changes
  • drug dependence
  • agitation
  • euphoria
  • depression
  • aggressive behavior
  • accommodation disorder
  • diplopia
  • blurred vision
  • visual changes
  • angina
  • hemorrhoids
  • orthostatic hypotension
  • hypotension
  • upper respiratory infection
  • acute respiratory insufficiency
  • lower respiratory infection
  • xerostomia
  • stomatitis
  • dyspepsia
  • constipation
  • hepatocellular damage
  • cholestasis
  • urinary tract infection
  • arthralgia
  • back pain
  • myalgia
  • altered consciousness
  • drowsy
  • sedation hangover effect
  • concentration difficulty
  • memory impairment
  • stupor
  • hallucinations
  • vertigo
  • dizziness
  • fatigue
  • flu-like symptoms
  • hyperhidrosis
  • ataxia
  • skin rash
  • pallor
  • anorexia
  • headache disorder
  • chest pain
  • hiccups
  • nausea
  • vomiting
  • tenesmus
  • diarrhea
  • abnormal hepatic function tests
  • CNS depression
  • nervousness
  • anaphylaxis
  • angioedema
  • lethargy
  • general weakness
  • malaise
  • irritability
  • accidental fall
  • acute abdominal pain
  • complex sleep behavior
  • dream disorder
  • sleep walking disorder
  • symptoms of anxiety
  • disturbance in thinking

Drug Interactions

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

A product that may interact with this drug is: sodium oxybate.

Other medications can affect the removal of zolpidem from your body, which may affect how zolpidem works. Examples include azole antifungals (such as ketoconazole), rifampin, St. John's Wort, among others.

The risk of serious side effects (such as slow/shallow breathing, severe drowsiness/dizziness) may be increased if this medication is taken with other products that may also cause drowsiness or breathing problems. Tell your doctor or pharmacist if you are taking other products such as opioid pain or cough relievers (such as codeine, hydrocodone), alcohol, marijuana (cannabis), other drugs for sleep or anxiety (such as alprazolam, lorazepam, zopiclone), muscle relaxants (such as carisoprodol, cyclobenzaprine), or antihistamines (such as cetirizine, diphenhydramine).

Check the labels on all your medicines (such as allergy or cough-and-cold products) because they may contain ingredients that cause drowsiness. Ask your pharmacist about using those products safely.