Wellbutrin XL


Wellbutrin XL Side Effects

See also Warning section.

Dry mouth, sore throat, dizziness, nausea, vomiting, ringing in the ears, headache, decreased appetite, weight loss, constipation, trouble sleeping, increased sweating, or shaking (tremor) may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

An empty tablet shell may appear in your stool. This effect is harmless because your body has already absorbed the medication.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

This medication may raise your blood pressure. Check your blood pressure regularly and tell your doctor if the results are high.

Tell your doctor right away if you have any serious side effects, including: fast/pounding/irregular heartbeat, mental/mood changes (such as anxiety, agitation, confusion, unusual behavior/thinking, memory loss), unusual weight loss or gain.

Stop taking bupropion and get medical help right away if you have any very serious side effects, including: seizure, eye pain/swelling/redness, widened pupils, vision changes (such as seeing rainbows around lights at night, blurred vision).

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), painful sores in the mouth/around the eyes, severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
  • infection
  • hypoglycemic disorder
  • SIADH syndrome
  • hyponatremia
  • pancytopenia
  • anemia
  • thrombocytopenic disorder
  • leukopenia
  • leukocytosis
  • drug-induced psychosis
  • acute confusion
  • manic disorder
  • hypomania
  • delusional disorder
  • paranoid disorder
  • panic disorder
  • suicidal
  • suicidal ideation
  • homicidal ideation
  • libido changes
  • disorder of ejaculation
  • bruxism
  • agitation
  • euphoria
  • aggressive behavior
  • hostility
  • behavioral disorders
  • parkinsonism
  • myoclonus
  • tardive dyskinesia
  • migraine
  • ocular hypertension
  • accommodation disorder
  • blurred vision
  • dry eye
  • mydriasis
  • tinnitus
  • hearing disorder
  • hearing loss
  • hypertension
  • acute myocardial infarction
  • pulmonary thromboembolism
  • complete atrioventricular block
  • atrioventricular block
  • extrasystoles
  • cardiac arrhythmia
  • orthostatic hypotension
  • hypotension
  • ecchymosis
  • pharyngitis
  • rhinitis
  • pneumonia
  • bronchitis
  • bronchospastic pulmonary disease
  • gingival bleeding
  • sialorrhea
  • xerostomia
  • stomatitis
  • esophagitis
  • gastric ulcer
  • dyspepsia
  • colitis
  • constipation
  • hepatitis
  • gastrointestinal hemorrhage
  • cystitis
  • erectile dysfunction
  • gynecomastia
  • salpingitis
  • vaginitis
  • abnormal vaginal bleeding
  • menstrual disorder
  • skin photosensitivity
  • erythema multiforme
  • Stevens-Johnson syndrome
  • exfoliative dermatitis
  • pruritus of skin
  • alopecia
  • hirsutism
  • dry skin
  • urticaria
  • arthralgia
  • neck pain
  • rhabdomyolysis
  • muscle weakness
  • muscle rigidity
  • myalgia
  • cramps in legs
  • coma
  • drowsy
  • unconsciousness
  • concentration difficulty
  • delirium
  • hallucinations
  • syncope
  • seizure disorder
  • dizziness
  • insomnia
  • fever
  • hyperhidrosis

Drug Interactions

See also Precautions section.

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

Some products that may interact with this drug include: codeine, pimozide, tamoxifen.

Taking MAO inhibitors with this medication may cause a serious (possibly fatal) drug interaction. Avoid taking MAO inhibitors (isocarboxazid, linezolid, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, safinamide, selegiline, tranylcypromine) during treatment with this medication. Most MAO inhibitors should also not be taken for two weeks before and after treatment with this medication. Ask your doctor when to start or stop taking this medication.

This medication may interfere with certain medical/laboratory tests (including brain scan for Parkinson's disease, urine screening for amphetamines), possibly causing false results. Tell laboratory personnel and all your doctors you use this drug.