TADALAFIL

generic for ADCIRCA

Tadalafil Side Effects

Headache, stomach upset, back pain, muscle pain, stuffy nose, flushing, or dizziness may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

To reduce the risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Sexual activity may put extra strain on your heart, especially if you have heart problems. If you have heart problems and experience any of these serious side effects while having sex, stop and get medical help right away: severe dizziness, fainting, chest/jaw/left arm pain, nausea.

Rarely, sudden decreased vision, including permanent blindness, in one or both eyes (NAION) may occur. If this serious problem occurs, stop taking tadalafil and get medical help right away. You have a slightly greater chance of developing NAION if you have heart disease, diabetes, high cholesterol, certain other eye problems ("crowded disk"), high blood pressure, if you are over 50, or if you smoke.

Rarely, a sudden decrease or loss of hearing, sometimes with ringing in the ears and dizziness, may occur. Stop taking tadalafil and get medical help right away if these effects occur.

In the rare event you have a painful or prolonged erection lasting 4 or more hours, stop using this drug and get medical help right away, or permanent problems could occur.

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
  • migraine
  • retinal vascular occlusion
  • visual field defect
  • acquired chromatopsia
  • blurred vision
  • visual changes
  • vision loss
  • conjunctivitis
  • conjunctival hyperemia
  • eyelid edema
  • eye tearing
  • ocular pain
  • tinnitus
  • hearing loss
  • hypertension
  • acute myocardial infarction
  • angina
  • cerebrovascular accident
  • orthostatic hypotension
  • hypotension
  • pharyngitis
  • upper respiratory infection
  • nasal congestion
  • xerostomia
  • esophagitis
  • gastroesophageal reflux disease
  • gastritis
  • dyspepsia
  • rectal bleeding
  • kidney disease with reduction in glomerular filtration rate (GFR)
  • priapism
  • frequent erections
  • Stevens-Johnson syndrome
  • exfoliative dermatitis
  • pruritus of skin
  • urticaria
  • arthralgia
  • neck pain
  • back pain
  • myalgia
  • pain in extremities
  • drowsy
  • syncope
  • seizure disorder
  • vertigo
  • dizziness
  • insomnia
  • fatigue
  • hyperhidrosis
  • pain
  • hypesthesia
  • skin rash
  • peripheral edema
  • facial edema
  • flushing
  • headache disorder
  • epistaxis
  • palpitations
  • dyspnea
  • cough
  • chest pain
  • nausea
  • vomiting
  • dysphagia
  • loose stools
  • diarrhea
  • abnormal hepatic function tests
  • paresthesia
  • general weakness
  • acute abdominal pain
  • anterior ischemic optic neuropathy
  • transient global amnesia
  • tachycardia

Drug Interactions

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

A product that may interact with this drug is: riociguat.

Tadalafil can cause a serious drop in your blood pressure when used with nitrates, which can lead to dizziness, fainting, and rarely heart attack or stroke. Do not use tadalafil with any of the following: certain drugs used to treat chest pain/angina (nitrates such as nitroglycerin, isosorbide), recreational drugs called "poppers" containing amyl or butyl nitrite.

If you are also taking an alpha blocker medication (such as doxazosin, tamsulosin) to treat an enlarged prostate/BPH or high blood pressure, your blood pressure may get too low which can lead to dizziness or fainting. Your doctor may start treatment with a lower dose of tadalafil or adjust your alpha blocker medication to minimize your risk of low blood pressure.

Other medications can affect the removal of tadalafil from your body, which may affect how tadalafil works. Examples include azole antifungals (such as itraconazole, ketoconazole), macrolide antibiotics (such as clarithromycin, erythromycin), HIV protease inhibitors (such as fosamprenavir, ritonavir), hepatitis C virus protease inhibitors (such as boceprevir, telaprevir), rifampin, among others.

Do not take this medication with any other product that contains tadalafil or other similar medications used to treat erectile dysfunction-ED or pulmonary hypertension (such as sildenafil, vardenafil).
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