Levetiracetam

generic for Keppra

Levetiracetam Side Effects

Drowsiness, dizziness, unusual tiredness, or weakness may occur. These side effects are more common during the first 4 weeks and usually lessen as your body adjusts to the medication. If any of these effects last or get worse, tell your doctor or pharmacist promptly.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor right away if you have any serious side effects, such as: loss of coordination (such as difficulty walking and controlling muscles), mental/mood changes (such as irritability, aggression, agitation, anger, anxiety), signs of infection (such as sore throat that doesn't go away, fever, chills), signs of anemia (such as unusual tiredness that doesn't go away, pale skin, fast breathing, fast heartbeat), easy bruising/bleeding.

A small number of people who take anticonvulsants for any condition (such as seizures, bipolar disorder, pain) may experience depression, suicidal thoughts/attempts, or other mental/mood problems. Tell your doctor right away if you or your family/caregiver notice any unusual/sudden changes in your mood, thoughts, or behavior including signs of depression, suicidal thoughts/attempts, thoughts about harming yourself.

Levetiracetam can commonly cause a rash that is usually not serious. However, you may not be able to tell it apart from a rare rash that could be a sign of a severe reaction. Tell your doctor right away if you develop any rash.

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, such as: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
  • infection
  • hyponatremia
  • pancytopenia
  • anemia
  • thrombocytopenic disorder
  • agranulocytosis
  • leukopenia
  • neutropenic disorder
  • eosinophilia
  • lymphocytosis
  • drug-induced psychosis
  • mood changes
  • panic disorder
  • depersonalization
  • suicidal ideation
  • personality disorders
  • agitation
  • depression
  • aggressive behavior
  • hostility
  • behavioral disorders
  • hyperkinesis
  • chorea
  • diplopia
  • blurred vision
  • hypertension
  • ecchymosis
  • pharyngitis
  • rhinitis
  • sinusitis
  • nasal congestion
  • gastroenteritis
  • constipation
  • acute hepatic failure
  • hepatitis
  • acute pancreatitis
  • nephritis
  • acute renal failure
  • eczema
  • erythema multiforme
  • toxic epidermal necrolysis
  • Stevens-Johnson syndrome
  • pruritus of skin
  • alopecia
  • neck pain
  • rhabdomyolysis
  • muscle weakness
  • myalgia
  • drowsy
  • memory impairment
  • hallucinations
  • vertigo
  • dizziness
  • insomnia
  • fatigue
  • flu-like symptoms
  • pain
  • ataxia
  • dyskinesia
  • skin rash
  • anorexia
  • weight loss
  • headache disorder
  • cough
  • vomiting
  • diarrhea
  • abnormal hepatic function tests
  • nervousness
  • anaphylaxis
  • angioedema
  • paresthesia
  • general weakness
  • irritability
  • indifference
  • disturbance of attention
  • DRESS syndrome
  • symptoms of anxiety

Drug Interactions

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

A product that may interact with this drug is: orlistat.