Flucytosine

generic for Ancobon

Flucytosine Side Effects

Nausea, vomiting, or diarrhea may occur. See the How to Use section about how to reduce stomach upset. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor right away if any of these unlikely but serious side effects occur: signs of kidney problems (such as change in the amount of urine), signs of liver problems (such as persistent nausea/vomiting, stomach/abdominal pain, dark urine, yellowing eyes/skin), signs of anemia (such as unusual tiredness, fast breathing, pale skin, fast heartbeat), signs of infection (such as fever, chills, cough, persistent sore throat), signs of bleeding (such as easy bruising/bleeding, nose bleeds, bleeding gums, bloody/black/tarry stools, vomit that looks like coffee grounds), muscle weakness/cramping.

A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
  • hypoglycemic disorder
  • hypokalemia
  • pancytopenia
  • anemia
  • thrombocytopenic disorder
  • agranulocytosis
  • leukopenia
  • neutropenic disorder
  • eosinophilia
  • drug-induced psychosis
  • acute confusion
  • parkinsonism
  • peripheral neuropathy
  • hearing loss
  • acute myocardial infarction
  • ventricular arrhythmias
  • acute respiratory distress syndrome
  • xerostomia
  • duodenal ulcer
  • ulcerative colitis
  • enterocolitis
  • hepatic necrosis
  • hepatitis
  • gastrointestinal hemorrhage
  • skin photosensitivity
  • allergic dermatitis
  • toxic epidermal necrolysis
  • pruritus of skin
  • urticaria
  • sedation
  • hallucinations
  • seizure disorder
  • vertigo
  • fever
  • fatigue
  • ataxia
  • skin rash
  • hyperbilirubinemia
  • anorexia
  • headache disorder
  • dyspnea
  • chest pain
  • nausea
  • vomiting
  • diarrhea
  • abnormal hepatic function tests
  • paresthesia
  • hypoplastic anemia
  • acute abdominal pain
  • jaundice
  • pure red cell aplasia

Drug Interactions

The effects of some drugs can change if you take other drugs or herbal products at the same time. This can increase your risk for serious side effects or may cause your medications not to work correctly. These drug interactions are possible, but do not always occur. Your doctor or pharmacist can often prevent or manage interactions by changing how you use your medications or by close monitoring.

To help your doctor and pharmacist give you the best care, be sure to tell your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products) before starting treatment with this product. While using this product, do not start, stop, or change the dosage of any other medicines you are using without your doctor's approval.

Some products that may interact with this drug include: cytarabine, other drugs that may affect the kidneys (including NSAIDs such as ibuprofen or naproxen), other drugs that decrease bone marrow function or lower your number of blood cells or weaken the immune system (such as cancer chemotherapy, trimethoprim/sulfamethoxazole).

This medication may interfere with certain laboratory tests (including serum creatinine), possibly causing false test results. Make sure laboratory personnel and all your doctors know you use this drug.

This document does not contain all possible drug interactions. Keep a list of all the products you use. Share this list with your doctor and pharmacist to lessen your risk for serious medication problems.