Estradiol

generic for Alora

Estradiol Side Effects

See also Warning section.

Nausea/vomiting, bloating, diarrhea, breast tenderness, headache, or weight changes may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor right away if you have any serious side effects, including: mental/mood changes (such as depression, memory loss), breast lumps, unusual vaginal bleeding (such as spotting, breakthrough bleeding, prolonged/recurrent bleeding), increased or new vaginal irritation/itching/odor/discharge, severe stomach/abdominal pain, persistent nausea/vomiting, yellowing eyes/skin, dark urine, swelling hands/ankles/feet, increased thirst/urination.

This medication may rarely cause serious problems from blood clots (such as heart attacks, strokes, deep vein thrombosis, pulmonary embolism). Get medical help right away if you have any serious side effects, including: chest/jaw/left arm pain, unusual sweating, sudden/severe headache, weakness on one side of the body, confusion, slurred speech, sudden vision changes (such as partial/complete blindness), pain/redness/swelling of legs, tingling/weakness/numbness in the arms/legs, trouble breathing, coughing up blood, sudden dizziness/fainting.

A very serious allergic reaction to this product is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
  • vulvovaginal candidiasis
  • candidiasis
  • infection
  • uterine leiomyoma
  • malignant neoplasm of the ovary
  • endometrial carcinoma
  • neoplasm of breast
  • precocious puberty
  • hypertriglyceridemia
  • hypercalcemia
  • body fluid retention
  • dementia
  • libido changes
  • depression
  • migraine
  • retinal thrombosis
  • hypertension
  • acute myocardial infarction
  • pulmonary thromboembolism
  • cerebrovascular accident
  • thromboembolic disorder
  • deep venous thrombosis
  • gallbladder obstruction
  • gynecomastia
  • mastalgia
  • nipple discharge
  • vaginitis
  • endometrial hyperplasia
  • vaginal discharge
  • vaginal irritation
  • dysmenorrhea
  • abnormal vaginal bleeding
  • genital organ pruritus
  • pruritus of skin
  • acne vulgaris
  • urticaria
  • chloasma
  • back pain
  • cramps
  • insomnia
  • weight gain
  • headache disorder
  • diarrhea
  • abdominal pain with cramps
  • abdominal distension
  • pelvic pain
  • anaphylaxis
  • angioedema
  • hypersensitivity drug reaction
  • general weakness

Drug Interactions

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

Some products that may interact with this drug include: aromatase inhibitors (such as anastrozole, exemestane, letrozole), fulvestrant, ospemifene, raloxifene, tamoxifen, toremifene, tranexamic acid.

This medication may interfere with certain laboratory tests, possibly causing false test results. Make sure laboratory personnel and all your doctors know you use this drug.