Claravis Side Effects

Dry lips and mouth, minor swelling of the eyelids or lips, crusty skin, nosebleeds, upset stomach, or thinning of hair may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

To relieve dry mouth, suck on (sugarless) hard candy or ice chips, chew (sugarless) gum, drink water, or use a saliva substitute.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor right away if you have any serious side effects, including: mental/mood changes (such as depression, anxiety, thoughts of suicide), tingling feeling in the skin, back/joint/muscle pain, signs of infection (e.g., fever, persistent sore throat), painful swallowing, peeling skin on palms/soles.

Isotretinoin may rarely cause disease of the pancreas (pancreatitis) that may rarely be fatal. Stop taking this medication and tell your doctor right away if you develop: severe stomach pain, severe or persistent nausea/vomiting.

Stop taking this medication and tell your doctor right away if you develop these unlikely but very serious side effects: severe headache, vision changes, ringing in the ears, hearing loss, chest pain, yellowing eyes/skin, dark urine, severe diarrhea, rectal bleeding.

A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
  • hypertriglyceridemia
  • hyperlipidemia
  • anemia
  • thrombocytopenic disorder
  • agranulocytosis
  • neutropenic disorder
  • drug-induced psychosis
  • mood changes
  • suicidal
  • suicidal ideation
  • libido changes
  • depression
  • aggressive behavior
  • idiopathic intracranial hypertension
  • cataracts
  • photophobia
  • acquired chromatopsia
  • night blindness
  • blurred vision
  • reduced visual acuity
  • corneal opacity
  • conjunctivitis
  • eyelid edema
  • dry eye
  • eye tearing
  • optic neuritis
  • ocular inflammation
  • ocular irritation
  • ocular itching
  • tinnitus
  • hearing loss
  • cerebrovascular accident
  • thromboembolic disorder
  • pharyngitis
  • upper respiratory infection
  • dry nose
  • bronchospastic pulmonary disease
  • gingivitis
  • gingival bleeding
  • xerostomia
  • cheilitis
  • cheilosis
  • esophageal ulcer
  • inflammatory bowel disease
  • hepatitis
  • acute pancreatitis
  • glomerulonephritis
  • hematuria
  • erectile dysfunction
  • irregular menstrual periods
  • menstrual disorder
  • paronychia
  • pyogenic granuloma
  • skin and skin structure infection
  • skin inflammation
  • skin photosensitivity
  • erythema multiforme
  • toxic epidermal necrolysis
  • Stevens-Johnson syndrome
  • abnormal desquamation
  • pruritus of skin
  • alopecia
  • hirsutism
  • dry skin
  • dyschromia
  • skin hypopigmentation
  • arthralgia
  • neck pain
  • back pain
  • tendonitis
  • rhabdomyolysis
  • muscle rigidity
  • myalgia
  • osteoporosis
  • osteopenia
  • premature epiphyseal closure
  • bone tenderness
  • skeletal hyperostosis
  • drowsy
  • seizure disorder
  • dizziness
  • fatigue
  • hyperhidrosis
  • skin rash
  • edema
  • anorexia
  • weight loss
  • headache disorder
  • epistaxis
  • palpitations
  • lymphadenopathy
  • nausea
  • hyperuricemia
  • hyperglycemia
  • proteinuria
  • abnormal hepatic function tests
  • nervousness
  • impaired wound healing
  • anaphylaxis
  • malaise

Drug Interactions

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

Some products that may interact with this drug are: tetracyclines (such as minocycline, tetracycline), vitamin A-type drugs (such as acitretin, bexarotene), vitamin A, drugs that cause bone loss (for example, anti-seizure drugs such as phenytoin, corticosteroids such as prednisone).

Tell your doctor when you start any new drug, and discuss if you should use additional reliable birth control. Also tell your doctor if you have any new spotting or breakthrough bleeding, because these may be signs that your birth control is not working well. (See also Warning section.)