Azelastine Side Effects

A bitter taste in the mouth, drowsiness, a burning feeling inside the nose, sneezing fits, cough, nose bleeds, runny nose, nausea, dry mouth, headache, weight gain, muscle aches, or red eyes may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
  • acute confusion
  • depression
  • hyperkinesis
  • blurred vision
  • visual changes
  • conjunctivitis
  • dry eye
  • eye tearing
  • ocular pain
  • hypertension
  • atrial fibrillation
  • pharyngitis
  • rhinitis
  • nasal passage irritation
  • lesion of nasal mucosa
  • bronchospastic pulmonary disease
  • toothache
  • xerostomia
  • stomatitis
  • aphthous stomatitis
  • glossitis
  • gastroenteritis
  • constipation
  • hematuria
  • furunculosis
  • contact dermatitis
  • eczema
  • pruritus of skin
  • folliculitis
  • myalgia
  • drowsy
  • dizziness
  • sleep disorder
  • fatigue
  • dysgeusia
  • parosmia
  • hypesthesia
  • skin rash
  • facial edema
  • flushing
  • weight gain
  • increased appetite
  • headache disorder
  • epistaxis
  • sneezing
  • palpitations
  • dyspnea
  • cough
  • chest pain
  • nausea
  • vomiting
  • diarrhea
  • urinary retention
  • nervousness
  • lacerations
  • anaphylaxis
  • paresthesia
  • dysesthesia
  • loss of sense of smell
  • symptoms of anxiety
  • tachycardia

Drug Interactions

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

Tell your doctor or pharmacist if you are taking other products that cause drowsiness such as opioid pain or cough relievers (such as codeine, hydrocodone), alcohol, marijuana (cannabis), drugs for sleep or anxiety (such as alprazolam, lorazepam, zolpidem), muscle relaxants (such as carisoprodol, cyclobenzaprine), or other antihistamines (such as cetirizine, diphenhydramine).

Check the labels on all your medicines (such as allergy or cough-and-cold products) because they may contain ingredients that cause drowsiness. Ask your pharmacist about using those products safely.