Arranon Side Effects

See also Warning section.

Headache, nausea, vomiting, loss of appetite, constipation, diarrhea, cough, shortness of breath, dizziness, drowsiness, and tiredness may occur. In some cases, your doctor may prescribe medication to prevent or relieve nausea and vomiting. Eating several small meals, not eating before treatment, or limiting activity may help lessen some of these effects. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

People using this medication may have serious side effects. However, your doctor has prescribed this drug because he or she has judged that the benefit to you is greater than the risk of side effects. Careful monitoring by your doctor may decrease your risk.

Tell your doctor right away if you have any serious side effects, including: easy bruising/bleeding, swelling ankles/feet.

This medication can lower the body's ability to fight an infection. Tell your doctor promptly if you develop any signs of an infection such as fever, chills, or persistent sore throat.

Nelarabine sometimes causes side effects due to the rapid destruction of cancer cells (tumor lysis syndrome). To lower your risk, your doctor may add a medication and tell you to drink plenty of fluids. Tell your doctor right away if you have symptoms such as: low back/side pain (flank pain), signs of kidney problems (such as painful urination, pink/bloody urine, change in the amount of urine), muscle spasms/weakness.

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any of the following symptoms of a serious allergic reaction: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
  • opportunistic fungal infection
  • infection
  • severe infection
  • hypoglycemic disorder
  • hypoalbuminemia
  • hypomagnesemia
  • hypocalcemia
  • dehydration
  • hypokalemia
  • anemia
  • thrombocytopenic disorder
  • leukopenia
  • neutropenic disorder
  • acute confusion
  • depression
  • demyelination
  • paralysis
  • peripheral neuropathy
  • peripheral motor neuropathy
  • blurred vision
  • sinus tachycardia
  • hypotension
  • sinusitis
  • pneumonia
  • pleural effusions
  • stomatitis
  • constipation
  • arthralgia
  • back pain
  • rhabdomyolysis
  • muscle weakness
  • myalgia
  • pain in extremities
  • drowsy
  • memory impairment
  • altered mental status
  • seizure disorder
  • dizziness
  • insomnia
  • fever
  • fatigue
  • pain
  • chills
  • tremor
  • dysgeusia
  • gait abnormality
  • ataxia
  • hypesthesia
  • edema
  • peripheral edema
  • hyperbilirubinemia
  • petechiae
  • anorexia
  • headache disorder
  • epistaxis
  • wheezing
  • dyspnea
  • cough
  • chest pain
  • nausea
  • vomiting
  • diarrhea
  • abdominal pain with cramps
  • abdominal distension
  • hyperglycemia
  • abnormal hepatic function tests
  • paresthesia
  • dysesthesia
  • general weakness
  • acute cerebellar syndrome
  • chemotherapy-induced hyperuricemia
  • increased creatine kinase level
  • progressive multifocal leukoencephalopathy
  • peripheral demyelinating neuropathy
  • peripheral sensory neuropathy

Drug Interactions

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

Some products that may interact with this drug include: other anti-cancer drugs (especially pentostatin).

Tell your doctor or pharmacist if you are taking other products that cause drowsiness such as opioid pain or cough relievers (such as codeine, hydrocodone), alcohol, marijuana (cannabis), drugs for sleep or anxiety (such as alprazolam, lorazepam, zolpidem), muscle relaxants (such as carisoprodol, cyclobenzaprine), or antihistamines (such as cetirizine, diphenhydramine).

Check the labels on all your medicines (such as allergy or cough-and-cold products) because they may contain ingredients that cause drowsiness. Ask your pharmacist about using those products safely.