Arimidex Side Effects

Hot flashes, headache, trouble sleeping, dizziness, stomach upset, nausea/vomiting, constipation, diarrhea, loss of appetite, weight gain, tiredness/weakness, increased coughing, or sore throat may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor right away if you have any serious side effects, including: bone pain, easily broken bones, joint stiffness/pain, muscle pain/stiffness, mental/mood changes (such as depression), numb/tingling skin, swelling hands/ankle/feet, shortness of breath, unusual vaginal discharge/bleeding/burning/itching/odor, pain/redness/swelling of arms or legs, vision changes, signs of liver disease (such as nausea/vomiting that doesn't stop, stomach/abdominal pain, yellowing eyes/skin, dark urine).

Get medical help right away if you have any very serious side effects, including: chest/jaw/left arm pain, confusion, trouble speaking, weakness on one side of the body.

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
  • arthritis
  • hypercholesterolemia
  • hypercalcemia
  • anemia
  • leukopenia
  • acute confusion
  • mood changes
  • depression
  • carpal tunnel syndrome
  • cataracts
  • hypertension
  • angina
  • myocardial ischemia
  • thromboembolic disorder
  • thrombophlebitis
  • pharyngitis
  • rhinitis
  • sinusitis
  • xerostomia
  • dyspepsia
  • gastrointestinal irritation
  • constipation
  • hepatitis
  • urinary tract infection
  • mastalgia
  • vaginal discharge
  • vaginal dryness
  • abnormal vaginal bleeding
  • erythema multiforme
  • Stevens-Johnson syndrome
  • pruritus of skin
  • alopecia
  • urticaria
  • arthralgia
  • back pain
  • myalgia
  • osteoporosis
  • bone pain
  • drowsy
  • dizziness
  • insomnia
  • flu-like symptoms
  • hyperhidrosis
  • pain
  • skin rash
  • peripheral edema
  • hyperbilirubinemia
  • flushing
  • weight gain
  • headache disorder
  • dyspnea
  • cough
  • chest pain
  • nausea
  • vomiting
  • diarrhea
  • abdominal pain with cramps
  • pelvic pain
  • abnormal hepatic function tests
  • fracture
  • anaphylaxis
  • angioedema
  • paresthesia
  • vulvovaginitis
  • general weakness
  • jaundice
  • lymphedema
  • trigger finger
  • drug-induced hot flash

Drug Interactions

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

Some products that may interact with this drug are: estrogens, tamoxifen, tibolone.