Amiloride

generic

Amiloride Side Effects

See also Warning section.

Headache, dizziness, nausea, vomiting, loss of appetite, stomach/abdominal pain, gas, or diarrhea may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

When given with other diuretics, amiloride may cause a loss of too much body water (dehydration) and salt/minerals. Tell your doctor right away if you have any of these unlikely but serious symptoms of dehydration or mineral loss: very dry mouth, extreme thirst, muscle cramps, weakness, fast heartbeat, severe dizziness, confusion, fainting, seizures.

Tell your doctor right away if any of these rare but serious side effects occur: signs of kidney problems (such as change in the amount of urine), yellowing eyes/skin, dark urine, persistent nausea/vomiting.

A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any of the following symptoms of a serious allergic reaction: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
  • hyponatremia
  • hyperkalemia
  • aplastic anemia
  • neutropenic disorder
  • acute confusion
  • abnormal sexual function
  • libido changes
  • depression
  • encephalopathy
  • ocular hypertension
  • visual changes
  • tinnitus
  • angina
  • cardiac arrhythmia
  • orthostatic hypotension
  • nasal congestion
  • xerostomia
  • gastrointestinal irritation
  • constipation
  • gastrointestinal hemorrhage
  • bladder irritability
  • erectile dysfunction
  • gynecomastia
  • pruritus of skin
  • alopecia
  • arthralgia
  • neck pain
  • back pain
  • cramps
  • drowsy
  • vertigo
  • dizziness
  • insomnia
  • fatigue
  • tremor
  • skin rash
  • anorexia
  • polydipsia
  • headache disorder
  • palpitations
  • dyspnea
  • cough
  • chest pain
  • nausea
  • vomiting
  • heartburn
  • flatulence
  • diarrhea
  • dysuria
  • increased urinary frequency
  • polyuria
  • abnormal hepatic function tests
  • nervousness
  • anaphylaxis
  • paresthesia
  • general weakness
  • acute abdominal pain
  • jaundice
  • leg pain

Drug Interactions

See also Precautions section.

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

Some products that may interact with this drug are: lithium, sodium phosphate products, other products that may increase potassium levels (such as eplerenone, tacrolimus, cyclosporine, birth control pills containing drospirenone, potassium-sparing diuretics like spironolactone/triamterene, ACE inhibitors like benazepril/captopril, angiotensin receptor antagonists like losartan/valsartan).

Some products have ingredients that could raise your blood pressure or worsen your heart failure. Tell your pharmacist what products you are using, and ask how to use them safely (especially cough-and-cold products, diet aids, or NSAIDs such as ibuprofen/naproxen).

This medication may interfere with certain laboratory tests (including glucose tolerance testing), possibly causing false test results. Make sure laboratory personnel and all your doctors know you use this drug.