Alprazolam XR

brand

Alprazolam XR Side Effects

See also Warning section.

Drowsiness, dizziness, increased saliva production, nausea, constipation, or change in sex drive/ability may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

To minimize dizziness and lightheadedness, get up slowly when rising from a seated or lying position.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor right away if any of these unlikely but serious side effects occur: mental/mood changes (such as hallucinations, thoughts of suicide), slurred speech or difficulty talking, loss of coordination, trouble walking, memory problems.

Get medical help right away if these rare but very serious side effects occur: yellowing eyes or skin, seizures.

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
  • hyperprolactinemia
  • acute confusion
  • manic disorder
  • hypomania
  • depersonalization
  • abnormal sexual function
  • libido changes
  • nightmares
  • agitation
  • depression
  • behavioral disorders
  • blurred vision
  • visual changes
  • hypotension
  • nasal congestion
  • respiratory depression
  • sialorrhea
  • xerostomia
  • dyspepsia
  • constipation
  • hepatic failure
  • drug-induced hepatitis
  • gynecomastia
  • galactorrhea not associated with childbirth
  • dysmenorrhea
  • premenstrual syndrome
  • menstrual disorder
  • allergic dermatitis
  • Stevens-Johnson syndrome
  • pruritus of skin
  • arthralgia
  • back pain
  • muscle spasm
  • muscle weakness
  • myalgia
  • pain in extremities
  • cramps
  • drowsy
  • sedation
  • concentration difficulty
  • memory impairment
  • seizure disorder
  • vertigo
  • dizziness
  • insomnia
  • fatigue
  • hyperhidrosis
  • tremor
  • muscle fasciculation
  • ataxia
  • dyskinesia
  • hypesthesia
  • skin rash
  • peripheral edema
  • anorexia
  • weight gain
  • weight loss
  • appetite changes
  • headache disorder
  • slurred speech
  • dysarthria
  • palpitations
  • hyperventilation
  • dyspnea
  • chest pain
  • nausea and vomiting
  • diarrhea
  • dysuria
  • urinary retention
  • abnormal hepatic function tests
  • nervousness
  • angioedema
  • paresthesia
  • lethargy
  • general weakness
  • malaise
  • irritability
  • acute abdominal pain
  • sensation of warmth
  • hypersomnia
  • dream disorder
  • acquired dystonia
  • disturbance of attention
  • increased libido
  • symptoms of anxiety

Drug Interactions

See also Warning section.

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

Some products that may interact with this drug include: kava, sodium oxybate.

Other medications can affect the removal of alprazolam from your body, which may affect how alprazolam works. Examples include azole antifungals (such as itraconazole, ketoconazole), cimetidine, certain anti-depressants (such as fluoxetine, fluvoxamine, nefazodone), drugs to treat HIV (delavirdine, protease inhibitors such as indinavir), macrolide antibiotics (such as erythromycin), rifamycins (such as rifabutin), St. John's wort, drugs used to treat seizures (such as phenytoin), among others.

The risk of serious side effects (such as slow/shallow breathing, severe drowsiness/dizziness) may be increased if this medication is taken with other products that may also cause drowsiness or breathing problems. Tell your doctor or pharmacist if you are taking other products such as opioid pain or cough relievers (such as codeine, hydrocodone), alcohol, marijuana (cannabis), other drugs for sleep or anxiety (such as diazepam, lorazepam, zolpidem), muscle relaxants (such as carisoprodol, cyclobenzaprine), or antihistamines (such as cetirizine, diphenhydramine).

Check the labels on all your medicines (such as allergy or cough-and-cold products) because they may contain ingredients that cause drowsiness. Ask your pharmacist about using those products safely.

Cigarette smoking decreases blood levels of this medication. Tell your doctor if you smoke or if you have recently stopped smoking.