Alkeran Warnings

Although melphalan is used to treat cancer, it may rarely increase your risk of developing other cancers. Also, melphalan may cause a severe decrease in your blood cells, which lowers your ability to fight infections and increases the risk of anemia/bleeding problems. You may be more likely to get a serious (rarely fatal) infection or any infection you have may get worse. Tell your doctor right away if you develop unusual growths or lumps, swollen glands, signs of infection (such as a sore throat that doesn't go away, fever, chills), easy or unusual bruising/bleeding, or unusual tiredness.

Taking melphalan during pregnancy may increase the risk of birth defects. Also, it may make it harder for men or women to have a child (decreased fertility) after treatment.

Talk with your doctor about the risks and benefits of treatment with this medication.
  • Pregnant women should avoid contact with this medication.
  • If you are pregnant or of childbearing age, discuss the risks/benefits of this medication with your doctor and pharmacist.
  • Warning: Breastfeeding is not recommended while using this drug. Consult your doctor or pharmacist.
  • Keep in refrigerator. Do not freeze.
  • CAUTION. Follow procedures for proper handling and disposal of hazardous drugs.
  • Read the boxed warning information for this medication.

Lactation Warnings


Pregnancy Warnings

  • Insufficient human data available. Based on drug pharmacology developmental toxicity is possible. Animal data suggest developmental toxicity at doses less than the recommended human dose. Inform pregnant patient of the possible risk to a fetus.