Actemra

brand

Actemra Side Effects

See also Warning section.

Headache or pain/redness/swelling at the injection site may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor right away if you have any serious side effects, including: stomach/abdominal pain.

Tocilizumab has rarely caused very serious (possibly fatal) liver disease. This effect may occur months to years after starting this medication. Tell your doctor right away if you develop symptoms of liver disease, such as nausea/vomiting that doesn't stop, loss of appetite, yellowing eyes/skin, dark urine.

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
  • active tuberculosis
  • bacterial sepsis
  • herpes zoster
  • herpes simplex infection
  • candidiasis
  • coccidioidomycosis
  • histoplasmosis
  • blastomycosis
  • aspergillosis
  • opportunistic fungal infection
  • Pneumocystis jirovecii pneumonia
  • infection
  • malignancy
  • hypothyroidism
  • hypercholesterolemia
  • hypertriglyceridemia
  • hyperlipidemia
  • thrombocytopenic disorder
  • leukopenia
  • neutropenic disorder
  • multiple sclerosis
  • conjunctivitis
  • hypertension
  • pharyngitis
  • upper respiratory infection
  • pneumonia
  • bronchitis
  • stomatitis
  • gastric ulcer
  • gastritis
  • gastroenteritis
  • diverticulitis of gastrointestinal tract
  • acute hepatic failure
  • hepatocellular damage
  • kidney stone
  • urinary tract infection
  • Stevens-Johnson syndrome
  • erythema
  • pruritus of skin
  • urticaria
  • septic arthritis
  • dizziness
  • skin rash
  • peripheral edema
  • hyperbilirubinemia
  • weight gain
  • headache disorder
  • dyspnea
  • cough
  • abnormal hepatic function tests
  • anaphylaxis
  • hypersensitivity drug reaction
  • injection site sequelae
  • reactivated tuberculosis
  • gastrointestinal perforation
  • pancreatitis
  • upper abdominal pain
  • cellulitis
  • peripheral demyelinating neuropathy
  • increased alanine transaminase
  • increased aspartate transaminase

Drug Interactions

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

Some products that may interact with this drug include: other drugs that can affect the immune system (such as certolizumab).

This medication can speed up the removal of other medications from your body, which may affect how they work. Examples of affected drugs include some cholesterol drugs such as atorvastatin/lovastatin/simvastatin, omeprazole, warfarin, among others.

This medication may decrease the effectiveness of hormonal birth control such as pills, patch, or ring. This could cause pregnancy. Discuss with your doctor or pharmacist if you should use additional reliable birth control methods while using this medication. Also tell your doctor if you have any new spotting or breakthrough bleeding, because these may be signs that your birth control is not working well.