Abraxane

brand

Abraxane Side Effects

See also Warning section.

Nausea, vomiting, diarrhea, mouth sores, headache, muscle/joint pain, numbness/tingling/burning of the hands/feet, weakness, or dizziness may occur. If any of these effects persist or worsen, tell your doctor promptly.

Temporary hair loss may occur. Normal hair growth should return after treatment has ended.

People using this medication may have serious side effects. However, your doctor has prescribed this drug because he or she has judged that the benefit to you is greater than the risk of side effects. Careful monitoring by your doctor may decrease your risk.

Tell your doctor right away if you have any serious side effects, including: signs of anemia (e.g., unusual tiredness, pale skin), easy bruising/bleeding, fast/slow/irregular heartbeat, pain/redness/swelling/weakness of the arms/legs, calf pain/swelling that is warm to the touch, vision changes.

This medication may rarely irritate the vein it is given into or leak out of the vein and irritate the area. These effects may cause redness, pain, swelling, discoloration, or unusual skin reactions at the injection site, either while the drug is given or rarely 7 to 10 days later. If this drug has leaked out of a vein and caused a skin reaction in the past, you may rarely have a skin reaction in that same area when the drug is given again, even when it is given into another area. Tell your doctor right away of any unusual skin/injection site symptoms.

Get medical help right away if any of these rare but very serious side effects occur: chest/jaw/left arm pain, coughing up blood, fainting, weakness on one side of the body, slurred speech, confusion, sudden severe headache.

This medication contains albumin that comes from human blood. There is a very small chance that you may get infections from this medication (including viral infections such as hepatitis), even though careful screening of blood donors, special manufacturing processes, and many tests are all used to reduce this risk. Discuss the benefits and risks of treatment with your doctor. Tell your doctor right away if you develop any of the following: signs of infection (e.g., fever, chills, cough, persistent sore throat), signs of hepatitis (e.g., persistent nausea/vomiting, stomach/abdominal pain, yellowing eyes/skin, dark urine, increasing tiredness).

A very serious allergic reaction to this drug is rare. Do not restart this medication if you have previously stopped using it due to a serious allergic reaction. Get medical help right away if you notice any of the following symptoms of a serious allergic reaction: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing, flushing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
  • bacterial sepsis
  • oral candidiasis
  • infection
  • dehydration
  • pancytopenia
  • bone marrow depression
  • anemia
  • thrombocytopenic disorder
  • neutropenic disorder
  • peripheral neuropathy
  • cystoid macular edema
  • visual changes
  • conjunctivitis
  • eye tearing
  • optic neuropathy
  • hypertension
  • pulmonary thromboembolism
  • atrioventricular block
  • abnormal ECG
  • supraventricular tachycardia
  • cardiac arrest
  • bradycardia
  • chronic heart failure
  • transient cerebral ischemia
  • cerebrovascular accident
  • thrombotic disorder
  • hypotension
  • hemorrhage
  • upper respiratory infection
  • pneumonia
  • pneumothorax
  • interstitial pneumonitis
  • pulmonary fibrosis
  • stomatitis
  • ischemic colitis
  • intestinal perforation
  • hepatic necrosis
  • kidney disease with reduction in glomerular filtration rate (GFR)
  • toxic epidermal necrolysis
  • Stevens-Johnson syndrome
  • erythema
  • pruritus of skin
  • nail disorders
  • alopecia
  • arthralgia
  • myalgia
  • fever
  • fatigue
  • skin rash
  • edema
  • hyperbilirubinemia
  • anorexia
  • headache disorder
  • voice change
  • dyspnea
  • cough
  • chest pain
  • nausea
  • vomiting
  • diarrhea
  • abnormal hepatic function tests
  • anaphylaxis
  • hypersensitivity drug reaction
  • injection site sequelae
  • general weakness
  • extravasation injury
  • chemotherapy-induced hyperuricemia
  • hepatic encephalopathy
  • maculopapular rash
  • pancreatitis
  • cellulitis
  • cranial nerve disorder
  • increased aspartate transaminase

Drug Interactions

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

Some products that may interact with this drug include: other drugs that may decrease bone marrow function (e.g., azathioprine, trimethoprim/sulfamethoxazole).